Tadalafil in patients on antihypertensive medications: Does safety

Tadalafil under the name of Cialis is used to treat erectile dysfunction (impotence) and symptoms of benign prostatic hypertrophy (enlarged prostate). Another brand of tadalafil is Adcirca, which is used to treat pulmonary arterial hypertension and improve exercise capacity in men and women. Tadalafil (Adcirca) is used to improve the ability to exercise in people with pulmonary arterial hypertension (PAH; high blood pressure in the vessels carrying blood to the lungs, causing shortness of breath, dizziness, and tiredness). The data presented herein suggest that tadalafil can be safely used by healthy subjects and by patients with cardiovascular diseases. As with sildenafil, the use of tadalafil is contraindicated in patients receiving nitrate therapy because of the potential for significant hypotensive effects. tadalafil for high blood pressure In hypertensive subjects with uncontrolled blood pressure on two to four classes of antihypertensive agents ( n = 36) tadalafil reduced mean ABPM systolic and diastolic blood pressure by 7.5 mmHg (95% CI 5.4, 9.6; P 0.01) and 4.3 mmHg (95% CI 6.1, 8.9; P 0.01) compared with placebo. Tadalafil is a medicine that relaxes blood vessels and treats erectile dysfunction, benign prostatic hypertrophy, and pulmonary arterial hypertension. It can cause serious interactions with nitrates and other

The BPтАРlowering effect of tadalafil was also examined in all the preтАРspecified disease and dosing regimens groups. Patients with ED or BPH who were not on antihypertensive medications experienced significantly higher reductions in systolic and diastolic BP regardless of dosing regimen compared to placebo.

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